ALERT: Practice Announcement 2/7/25 – Our practice is actively monitoring the weather for the coming week. Please stay tuned to our website for the latest announcements or closures.      Exciting News! Our Gainesville Office has moved to Bristow9450 Innovation Drive, Manassas, VA 20110.  Same great providers and care team, same exceptional care, new, larger space to better serve our patients.

pNGVL4a-Sig/E7(detox)/HSP70 DNA vaccine

An antigen-specific DNA cancer vaccine consisting of the coding sequences of a signal peptide (pNGVL4a-Sig), a detox form of the human papillomavirus type 16 (HPV-16) antigen E7, and the heat shock protein 70 (HSP70). Upon administration, this vaccine may generate potent cytotoxic CD8(+) T-cell responses against E7-expressing tumor cells, resulting in tumor cell death. Check for active clinical trials using this agent. (NCI Thesaurus)

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