ALERT: Practice Announcement 2/11/25 – Practice Announcement: We will be OPEN on time on Wednesday, February 12, 2025. Please be safe and allow extra time. Thank you.      Exciting News! Our Gainesville Office has moved to Bristow9450 Innovation Drive, Manassas, VA 20110.  Same great providers and care team, same exceptional care, new, larger space to better serve our patients.

anti-CD20/CD3 monoclonal antibody REGN1979

A bispecific, human monoclonal antibody with potential antineoplastic activity. Anti-CD20/CD3 monoclonal antibody REGN1979 contains two antigen-recognition sites: one for human CD3, a T cell surface antigen, and one for human CD20, a tumor-associated antigen that is exclusively expressed on B-cells during most stages of B-cell development and is often overexpressed in B-cell malignancies. Upon administration, REGN1979 binds to both T-cells and CD20-expressing tumor B-cells, which cross-links the T-cells to tumor cells, and may result in a potent cytotoxic T-lymphocyte (CTL) response against CD20-expressing tumor B-cells. Check for active clinical trials using this agent. (NCI Thesaurus)

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