Exciting News! Our Gainesville Office is Moving to Bristow – November 11th! 9450 Innovation Drive, Manassas, VA 20110. Same great providers and care team. Same exceptional care. New, larger space to better serve our patients.
A synthetic N-methylpiperidinyl chlorophenyl flavone compound. As an inhibitor of cyclin-dependent kinase, alvocidib induces cell cycle arrest by preventing phosphorylation of cyclin-dependent kinases (CDKs) and by down-regulating cyclin D1 and D3 expression, resulting in G1 cell cycle arrest and apoptosis. This agent is also a competitive inhibitor of adenosine triphosphate activity. Check for active clinical trials using this agent. (NCI Thesaurus)