Isabelle Le, MD

Virginia Cancer Specialists Physicians

Isabelle Le, MD Headshot

Breast cancer touches the lives of so many every day. For women (and some men) with breast cancer, or pre-cancerous conditions of the breast, I provide compassionate, personalized, evidence-based, comprehensive care including cancer-prevention, treatment, and ideal supportive care.

Work and Credentials:

Primary Location

Arlington Office

Other Location

Arlington Infusion Suite


Medical Oncologist

Board Certification

Medical Oncology and Hematology


University of Texas Health Science Center at San Antonio

Medical School

Wayne State University School of Medicine


Hope College

Special Interests

Breast Cancer

Isabelle Le, MD, is board certified in Medical Oncology and Hematology. She is a member of the American Society of Clinical Oncology (ASCO). As a medical oncologist, Dr. Le has a strong focus in the treatment and management of breast cancer. As a breast specialist, Dr. Le works with a multidisciplinary team, which includes breast surgeons, radiation oncologists, nurse practitioners, physician assistants, nurse navigators, genetic counselors, clinical trials and research, dietitians and more.

Dr. Le received her medical degree from Wayne State University Medical School in Detroit, MI. She then completed residency training in internal medicine at Wayne State University – Detroit Medical Center. Finally, she completed a fellowship in hematology/oncology at the University of Texas Health Science Center in San Antonio. After completing her fellowship, she served as a medical oncologist with a focus in breast cancer at MyMichigan Health – affiliated with University of Michigan. Her research interests include clinical trials in metastatic and early staged breast cancer.

Dr. Le received the resident of the year award during her training. She was the physician champion for her oncology practice participating in the Michigan Oncology Quality Consortium, a physician led, voluntary collaborative of medical and gynecologic oncologists. She was the principle breast oncologist for several multidisciplinary breast cancer tumor boards and the Principle Investigator (PI) for several clinical trials focused on Breast Cancer.

In her spare time she loves to spend time with her husband and children. They enjoy traveling and tasting new cuisines. Dr. Le also enjoys cycling as a part of her weekly routine.

Dr. Le is fluent in Vietnamese.

Physician Publications

May 28, 2019

Temozolomide as a Single Agent Maintenance Therapy in Elderly Patients With Primary CNS Lymphoma

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October 1, 2012

Aquaporin-2 levels in vitro and in vivo are regulated by VACM-1, a cul 5 gene

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May 13, 2012

VACM-1/cul5 expression in vascular tissue in vivo is induced by water deprivation and its expression in vitro regulates aquaporin-1 concentrations

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More Publications by Isabelle Le, MD

November 9, 2009

Phosphorylation of VACM-1/Cul5 by protein kinase A regulates its neddylation and antiproliferative effect

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September 4, 2007

Expression of VACM-1/cul5 mutant in endothelial cells induces MAPK phosphorylation and maspin degradation and converts cells to the angiogenic phenotype.

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December 22, 2006

Estrogen-dependent growth and estrogen receptor (ER)-alpha concentration in T47D breast cancer cells are inhibited by VACM-1, a cul-5 gene

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Primary Location

Arlington Office Office

Arlington Office

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Other Locations