A synthetic derivative of inosinic acid with antiretroviral and immunomodulatory activities. Rintatolimod acts through a number of pathways to stimulate the antiviral activity of the immune system. This agent stimulates interferon production; activates the oligoadenylate synthase-RNase L pathway; stimulates natural killer cell activity; and acts as a non-mitogenic stimulator of the immune system. Rintatolimod also inhibits replication of the human immunodeficiency virus (HIV) in vitro. Check for active clinical trials using this agent. (NCI Thesaurus)

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