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A solution containing a non-toxic, fluorescent tricarbocyanine dye with a peak spectral absorption at 790 nm bound to the plasma protein albumin, that may be used in sentinel node mapping using a near infrared (NIR) imaging system. Upon injection of the indocyanine green (ICG)/albumin solution around the tumor, the ICG/albumin complex, travels though the vascular system. Using a NIR imaging system, the ICG, which emits light in the NIR range, permits the visualization of sentinel nodes and may help in cancer staging. Check for active clinical trials using this agent.
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