A phytochemical-based toothpaste containing Calendula officinalis, Plantago major, Cochlearia armoracia, Hamamelis virginiana with potential soothing activity. Calendula officinalis/Plantago major/Cochlearia armoracia/ Hamamelis virginiana herbal toothpaste may relieve the discomfort associated with radiation-induced mucositis. Check for active clinical trials using this agent. (NCI Thesaurus)