A proprietary lotion containing a blend of the four botanicals Allium cepa L. (Onion), Citrus limon L. (Citrus), Theobroma cacao L. (Cocoa), Paullinia cupana (Guarana), with potential activity against chemotherapy-induced alopecia (CIA). Upon administration to the scalp, botanical lotion CG428 may normalize the apoptotic process of hair follicular cells and reduce inflammation in the scalp. This may reverse CIA, restore the natural hair cycle, improve hair regrowth, and improve the psychosocial well-being of the affected patient. Check for active clinical trials using this agent. (NCI Thesaurus)