WEATHER ALERT January 27, 2026 (12:00 PM): Due to the recent inclement weather, we are experiencing higher than usual call volume. Your call is important to us. We strongly recommend current patients utilize the Patient Portal to reach their clinical teams with questions or to adjust their appointment if necessary. Messages received in the Patient Portal will be returned as quickly as possible. Thank you for your patience.
The orally available hydrochloride salt of pyrrolidine-3-carboxylic acid with potential antineoplastic activity. As a selective antagonist of the endothelin-A (ETA) receptor, atrasentan binds selectively to the ETA receptor, which may result in inhibition of endothelin-induced angiogenesis and tumor cell proliferation. Check for active clinical trials using this agent. (NCI Thesaurus)