Attention Gainesville Patients: With the LPGA Solheim Cup 2024 coming to the Robert Trent Jones Golf Club in Gainesville, Sept 10-15, please be advised that significant traffic and potential delays are expected in the area. We encourage you to plan your outings accordingly, leaving extra time for travel. Thank you.

anti-EGFR monoclonal antibody GC1118

A recombinant, human monoclonal antibody directed against the epidermal growth factor receptor (EGFR) with potential antineoplastic activity. Upon intravenous administration, GC1118 binds to and blocks the ligand binding site of EGFR, which prevents receptor dimerization and activation. This may lead to an inhibition of both EGFR-dependent downstream pathways and EGFR-dependent tumor cell proliferation and metastasis. EGFR, a receptor tyrosine kinase, may be overexpressed on the surfaces of various tumor cell types. Check for active clinical trials using this agent. (NCI Thesaurus)

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